1. It is of no use to try this method, since the problem is too big to handle. この問題は扱うのには大きすぎるので、この方法を試そうとしても無駄だ 2. It is of no use trying to convince her to do otherwise. She has already made up her mind. 彼女を説得しようとしても無駄だ。彼女はすでに決心している 3. It is of no use to speak to the boss about this. He won't listen. この件について上司に話しても無駄だ。彼は聞こうとしない。 4. It is of no use to complain now. The milk spilled everywhere. 今、文句を言っても無駄だ。覆水盆に返らず